Metalworking lubricants are related to various occupational diseases. Occupation diseases that are known to cause significant incidence rate include benign respiratory diseases (including asthma, pneumonia, etc.), allergic skin diseases and malignant tumors. The results of animal analysis showed that the fatty granulomas of alveolar and macrophages with fat would occur when dogs touched oil mist for more than 12 months, and the respiratory tissue changed. In 1996, 166 workers in a ball bearing factory using emulsion were investigated for asthma. The results showed that when the oil mist concentration in the workshop was 0.65rng/m3, 4% of the workers who often touched the oil mist of metalworking fluid had asthma; and the number of workers who did not touch the oil mist of processing liquid in the same factory was zero. Incidence rate incidence rate of skin diseases in full-time workers in 1991 is 0.77 per thousand, while the incidence of installation of screws and ordinary machinery processing industry in the same year is 3.33 per thousand and 2.22 per thousand respectively. These two industries are also the highest concentration of fog in the occupation environment.